Establishment and Goals of the NBRF Robert Ledley

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nbrf christmas tree showing projects , journals initiated organization 1991. @ base establishment of foundation in 1960. ornaments represent (moving bottom top , left right): atlas of protein sequence , structure (initiated in 1965), computers in biology , medicine (journal founded in 1969), pattern recognition (journal founded in 1967), first protein datatape (1972), acta (prototype built 1974), computer languages (journal founded in 1972), first nucleic acid datatape (1979), computerized medical imaging , graphics (journal founded in 1981 -- grew out of 1976 journal computerized tomography , 1977 journal computerized radiology), cenog (prototype built 1978), protein information resource (launched in 1984), 1990 nbrf s 30th year.


following survey work nas-nrc , publication of , lusted’s articles in science, ledley sought federal government , university support efforts development computers , computer programs use biomedical researchers. support of nas-nrc, ledley chartered in 1960 national biomedical research foundation (nbrf), nonprofit organization, based in nas-nrc-owned building near dupont circle, washington, d.c.


believing career university faculty member constrain research, ledley left position @ gwu in order dedicate full-time running nbrf. ledley lead nbrf until retirement in 2010. employees included: louis s. rotolo (ledley’s assistant in nas-nrc survey), james b. wilson (ledley’s former graduate student @ gwu), , margaret o. dayhoff (a quantum chemist ph.d. columbia , ledley’s childhood friend flushing).


grounded in ledley’s belief computer use substantially improve biology , medicine helping mathematize areas, nbrf’s mission “stimulate biomedical research scientists utilize computers setting example through own pioneering research , development in new areas of computer applications.” starting annual budget of under $100,000 , half-dozen employees, nbrf grew multimillion-dollar operation more 20 employees 1980s. vast majority of nbrf’s support came nih, 1980 drew support variety of federal, university, , corporate sources, in addition generating revenue through publication of journals , sale of electronic instruments, software, , patents.


in 1970, nbrf began affiliation georgetown university medical center. university, had allocated space biomedical computing facility had never been built, provided office , laboratory space nbrf, while nbrf serve computing resource university bring funding , prestige university through research , development activities.


as part of move, ledley appointed georgetown university’s faculty professor of radiology, physiology, , biophysics. nbrf physically located @ georgetown 1970 2006. between 2006 , 2010 based in offices in washington, d.c. , bethesda, md.


in 2011, nbrf reincorporated in massachusetts , has adopted new mission statement.








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